Chopped Biscuit Pizza Casserole

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Looking for a cozy, crowd-pleasing dinner that comes together with minimal effort? This Chopped Biscuit Pizza Casserole is the answer. With fluffy biscuit dough, gooey mozzarella, savory pepperoni, and rich pizza sauce baked to perfection, it’s everything you love about pizza in comforting casserole form.

Perfect for busy weeknights or weekend gatherings, this dish is endlessly customizable. Use it to clean out the fridge or tailor it to your favorite pizza toppings. It turns out golden, melty, and irresistibly satisfying every time.

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What Kind of Biscuits Should I Use?

Refrigerated canned biscuit dough is the key to ease and fluffiness in this casserole. You can use homestyle or buttermilk biscuits—both puff up beautifully and soak in the sauce. Avoid flaky layers if you want a cohesive, less-separated texture.

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Ingredients for the Chopped Biscuit Pizza Casserole

• 1 can (16 oz) refrigerated biscuit dough
• 1 cup pizza sauce
• 2 cups shredded mozzarella cheese
• 1/2 cup sliced pepperoni (or mini pepperoni)
• 1/2 teaspoon Italian seasoning
• 1/4 teaspoon crushed red pepper flakes (optional)
• 2 tablespoons grated Parmesan cheese
• 1 tablespoon olive oil
• 1/4 cup diced bell peppers (optional)
• 1/4 cup sliced black olives (optional)

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How To Make the Chopped Biscuit Pizza Casserole

Step 1: Prep the Oven and Pan

Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish or spray it with nonstick spray.

Step 2: Cut and Toss the Biscuits

Open the biscuit can and cut each biscuit into quarters. In a large bowl, toss the biscuit pieces with olive oil, Italian seasoning, and crushed red pepper flakes.

Step 3: Add the Sauce and Toppings

Pour in the pizza sauce and toss again until the biscuits are well coated. Mix in half the mozzarella, half the pepperoni, and any optional veggies you like.

Step 4: Layer and Top

Transfer the mixture into the prepared baking dish. Spread it out evenly. Sprinkle the remaining mozzarella, pepperoni, and Parmesan on top.

Step 5: Bake and Serve

Bake for 25–30 minutes or until the biscuits are golden and cooked through, and the cheese is bubbling. Let it cool for 5 minutes before serving.

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How to Serve and Store Chopped Biscuit Pizza Casserole

Serve this casserole warm with a side salad or some marinara for dipping. It’s a great centerpiece for game nights or casual family dinners.

To store leftovers, cover the dish or transfer slices into an airtight container and refrigerate for up to 4 days. Reheat in the oven at 350°F for best results, or microwave for a quick fix.

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Frequently Asked Questions

Can I make this ahead of time?

Yes, you can assemble the casserole a few hours in advance and refrigerate it until you’re ready to bake. Add 5 extra minutes to the baking time if chilled.

Can I freeze it?

You can freeze this dish after baking. Cool completely, wrap tightly, and freeze for up to 2 months. Reheat in the oven straight from frozen.

What other toppings can I use?

Feel free to use cooked sausage, bacon bits, mushrooms, spinach, or jalapeños. Just avoid adding too many wet ingredients to keep the biscuits from getting soggy.

Can I use crescent roll dough instead?

You can, but the texture will be different. Biscuits give more height and fluff; crescent rolls will be denser and more layered.

Is this kid-friendly?

Absolutely! It’s like eating pizza with a fork. You can even let kids help toss the ingredients.

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Want More Casserole Ideas?

If you love this Chopped Biscuit Pizza Casserole, you might also enjoy these easy comfort dishes:

• Taco Spaghetti Casserole for a bold Tex-Mex twist.
• Easy Tuna Noodle Casserole with Cream Cheese that’s creamy and nostalgic.
• Chicken Cordon Bleu Casserole for a cheesy, meaty bake.
• Sour Cream Beef Noodle Casserole that’s rich and hearty.
• Creamy Crockpot Chicken Spaghetti for set-it-and-forget-it ease.

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Save This Pin + Share Your Results

📌 Save this recipe to your Pinterest dinner board so you can always come back to it.

Tag me or comment below with your own twists! Did you sneak in veggies or go all-meat? Maybe try a BBQ sauce base instead of classic red?

I love seeing your spins on my comfort food classics. Let’s make dinner delicious together! For more recipes like this, visit my Pinterest at Nina Dishes.

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