Garlic Butter Chicken over Cheesy Cajun Rotini

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When I crave something comforting yet packed with flavor, this Garlic Butter Chicken over Cheesy Cajun Rotini always hits the mark. The combination of tender chicken pieces infused with garlicky richness and a creamy, cheesy rotini with a Cajun kick creates a dinner that’s both indulgent and satisfying. It’s one of those dishes I keep going back to, especially after a long day when I need something hearty but not too complicated.

The real magic of this dish lies in its balance of bold and comforting flavors. The garlic butter sauce enriches the chicken without overpowering the taste, while the rotini is smothered in a luscious cheese blend that perfectly holds onto the Cajun spices. Each bite offers a little heat, a little creaminess, and a whole lot of flavor.

I first made this dish for a casual dinner with friends, and it quickly became a fan favorite. Everyone was scooping up seconds and asking for the recipe. Since then, it’s become a staple in my kitchen, especially when I want something impressive but approachable. If you love bold pasta dishes like my Creamy Garlic Chicken Breasts, Creamy Cajun Steak Alfredo, or Garlic Butter Steak Bites with Cheesy Rigatoni, you’re going to adore this one.

Why You’ll Love This Garlic Butter Chicken over Cheesy Cajun Rotini

This recipe brings together the best of both worlds: the homey comfort of cheesy pasta and the bold flavor of Cajun-seasoned chicken. It’s quick enough for weeknights yet special enough for entertaining. The garlic butter adds a depth that makes it irresistible, and the creamy rotini is pure indulgence. Plus, it’s incredibly easy to customize to your spice preference or what you have on hand in the fridge.

Ingredients

Chicken breasts: Boneless, skinless pieces are ideal for quick cooking and soaking up the garlic butter flavor.

Garlic cloves: Fresh garlic brings that unmistakable aromatic richness.

Unsalted butter: This is the heart of the garlic butter sauce, giving it a luscious, silky base.

Cajun seasoning: Adds boldness and just the right amount of heat to elevate the whole dish.

Heavy cream: Brings creamy texture to the cheese sauce and balances the spices.

Cheddar cheese: Sharp and melty, perfect for coating the pasta in cheesy goodness.

Parmesan cheese: Adds a salty, nutty depth that pairs beautifully with the Cajun flavor.

Rotini pasta: Its spiral shape is perfect for holding onto that creamy, spicy cheese sauce.

Salt and pepper: Essential for seasoning and balancing the other flavors.

Olive oil: Helps to sear the chicken until golden brown while keeping it juicy.

How to Make Garlic Butter Chicken over Cheesy Cajun Rotini

Step 1: Sear the Chicken

Season the chicken breasts with salt, pepper, and Cajun seasoning. In a skillet, heat olive oil over medium-high and sear the chicken until golden on both sides and cooked through. Remove and set aside.

Step 2: Cook the Pasta

While the chicken cooks, boil the rotini in salted water until al dente. Drain and set aside, reserving about 1/2 cup of pasta water.

Step 3: Make the Garlic Butter Sauce

In the same skillet, lower the heat and add butter. Once melted, stir in the minced garlic and cook until fragrant. Deglaze the skillet with a splash of pasta water if needed to lift the browned bits.

Step 4: Create the Cheese Sauce

Pour in the heavy cream and bring to a simmer. Stir in cheddar and Parmesan cheeses until melted and smooth. Add more Cajun seasoning to taste.

Step 5: Combine and Serve

Add the cooked rotini to the cheese sauce, tossing to coat well. Slice the seared chicken and place on top. Garnish with a sprinkle of Parmesan and fresh herbs if desired. Serve hot and enjoy every creamy, garlicky bite!

Recipe Variations and Possible Substitutions

If you’re out of rotini, penne or fusilli will work just as well to hold onto the creamy sauce. Want to lighten things up? Swap the heavy cream for half-and-half, or even whole milk with a bit of cornstarch for thickness. You can also add vegetables like bell peppers or spinach for added nutrition and color. If you prefer more heat, mix in some red pepper flakes or a touch of cayenne with the Cajun seasoning.

Serving and Pairing Suggestions

Serve this dish alongside a crisp green salad or roasted vegetables for a balanced meal. Garlic bread or crusty French rolls make excellent accompaniments to scoop up the cheesy sauce. For drinks, a chilled glass of white wine or a light beer pairs beautifully with the bold Cajun flavors.

Storage and Reheating Tips

Store any leftovers in an airtight container in the refrigerator for up to 3 days. When reheating, add a splash of milk or cream to help loosen the sauce and stir well while warming on the stove or in the microwave. This dish can also be frozen for up to a month, though the texture of the pasta may soften slightly upon thawing.

FAQs

Can I make Garlic Butter Chicken over Cheesy Cajun Rotini ahead of time?

Yes, you can prepare the chicken and sauce ahead of time and store them separately. Cook the pasta fresh when you’re ready to serve for the best texture.

What kind of cheese works best in Garlic Butter Chicken over Cheesy Cajun Rotini?

A mix of cheddar and Parmesan offers a perfect balance of meltability and flavor. You can also use Monterey Jack or mozzarella if you want a milder taste.

Is Garlic Butter Chicken over Cheesy Cajun Rotini spicy?

The Cajun seasoning gives it a mild to moderate heat. You can adjust the amount or choose a mild version if you’re sensitive to spice.

Can I use leftover chicken for Garlic Butter Chicken over Cheesy Cajun Rotini?

Absolutely! Just slice or shred it and toss it into the cheese sauce to warm through before combining with the pasta.

Related Recipe You’ll Like

If you enjoyed this recipe, you’ll definitely want to try my One Pot Creamy Beef and Garlic Butter Pasta or the comforting Shipwreck Dinner for more cozy meals packed with flavor.

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