Comfort food gets a genius-level upgrade with this Mac and Cheese Meatloaf. It’s where creamy, cheesy pasta meets hearty meatloaf in one ultra-satisfying slice. Imagine a juicy meatloaf base layered with rich, gooey mac and cheese, baked to golden perfection. It’s the kind of dinner that makes everyone stop talking and start digging in.

Whether you’re cooking to impress or craving a creative way to use up leftovers, this dish brings big flavor with fun presentation. Perfect for family dinners, potlucks, or those nights when you want to serve something a little unexpected but totally familiar.

What Kind of Pasta Should I Use for the Mac and Cheese Layer?

Short pasta like elbow macaroni, shells, or cavatappi hold onto cheese sauce best. Elbow macaroni is a classic and gives the right bite without overpowering the meatloaf. You can also go for whole wheat or gluten-free versions if preferred.

Ingredients for the Mac and Cheese Meatloaf

2 pounds ground beef (80/20 preferred)
1/2 cup breadcrumbs
1/4 cup milk
1 large egg
1 small onion, finely chopped
2 teaspoons Worcestershire sauce
1 teaspoon garlic powder
Salt and pepper to taste
2 cups cooked elbow macaroni
1 1/2 cups shredded cheddar cheese
1/2 cup whole milk
2 tablespoons butter
1 tablespoon flour
1/2 teaspoon paprika
Fresh parsley, chopped (for garnish)

How To Make the Mac and Cheese Meatloaf

Step 1: Prep the Meatloaf Base

Preheat your oven to 375°F (190°C). In a large bowl, mix the ground beef, breadcrumbs, milk, egg, onion, Worcestershire sauce, garlic powder, salt, and pepper. Press the mixture into a loaf pan or shape it by hand on a lined baking sheet.

Step 2: Make the Cheese Sauce

While the meatloaf bakes, prepare your cheese sauce. In a saucepan, melt butter over medium heat. Whisk in flour and cook for 1 minute. Gradually whisk in milk and continue stirring until thickened. Add cheddar cheese and paprika, stirring until melted and smooth.

Step 3: Combine Pasta and Cheese

Stir the cooked macaroni into the cheese sauce until fully coated. Keep warm.

Step 4: Layer and Bake

After 30 minutes of baking, remove the meatloaf from the oven. Spoon the mac and cheese over the top, then return to the oven for an additional 10–15 minutes, until the top is bubbly and golden.

Step 5: Serve and Garnish

Let rest for 5 minutes before slicing. Garnish with fresh parsley and serve with a side salad or roasted veggies.

Serving and Storing This Mac and Cheese Meatloaf

Serve this hearty dish warm and sliced thick. Pair it with something fresh and green like a crisp Caesar salad or roasted Brussels sprouts. It also makes an indulgent leftover sandwich the next day—just toast a slice between two pieces of sourdough.

Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven at 350°F or microwave individual slices until hot.

Frequently Asked Questions

Can I use ground turkey or chicken instead of beef?

Absolutely. Just note that leaner meats may need a bit more moisture. Add a tablespoon of olive oil to keep it juicy.

Can I make it ahead of time?

Yes, you can assemble the meatloaf and the mac and cheese separately. Refrigerate and bake when ready.

Can I freeze this dish?

You can freeze the meatloaf (without the mac and cheese layer) for up to 2 months. Add the mac and cheese after reheating the base.

What cheese works best?

Sharp cheddar gives great flavor, but you can mix in mozzarella, Monterey Jack, or even a bit of Gruyère for richness.

How do I avoid greasy meatloaf?

Use 80/20 beef and bake on a rack or let the loaf rest on a paper towel before serving.

Can I make it spicy?

Definitely! Add a pinch of cayenne pepper to the cheese sauce or some diced jalapeños to the meat mixture.

Want More Dinner Ideas with a Twist?

If you enjoyed this Mac and Cheese Meatloaf, check out these comforting favorites:

Creamy Garlic Chicken Breasts for a savory skillet sensation.
Marry Me Chicken Pasta for creamy, tomato-kissed indulgence.
Cheesy Mexican Rice Casserole that brings bold, zesty flavor to the table.
One-Pot Creamy Beef and Garlic Butter Pasta when you’re craving comfort in one pan.
Sour Cream Beef Noodle Casserole for nostalgic, creamy coziness.

📌 Save this recipe to your Pinterest comfort food board so it’s right there when cravings hit: Nina Dishes on Pinterest.

And let me know in the comments—did you go spicy or classic? Did your kids eat it all before you got a bite? I love hearing how you make these recipes your own!

Questions or feedback? Drop them below and let’s help each other make dinnertime extra delicious.

Mac and Cheese Meatloaf

Author: Nina Klatten
Total Time: 65 minutes
Yield: 6 servings

Print Recipe

Description

Mac and Cheese Meatloaf is a two-in-one comfort food marvel. A savory, juicy meatloaf forms the base, topped with creamy, cheesy macaroni that’s baked until bubbly and golden. It’s a family favorite twist perfect for weeknight dinners or when you want to serve something unforgettable.

Instructions

1. Preheat your oven to 375°F (190°C). In a large bowl, mix the ground beef, breadcrumbs, milk, egg, onion, Worcestershire sauce, garlic powder, salt, and pepper. Press the mixture into a loaf pan or shape it by hand on a lined baking sheet.

2. In a saucepan, melt butter over medium heat. Whisk in flour and cook for 1 minute. Gradually whisk in milk and continue stirring until thickened. Add cheddar cheese and paprika, stirring until melted and smooth.

3. Stir the cooked macaroni into the cheese sauce until fully coated. Keep warm.

4. After 30 minutes of baking, remove the meatloaf from the oven. Spoon the mac and cheese over the top, then return to the oven for an additional 10–15 minutes, until the top is bubbly and golden.

5. Let rest for 5 minutes before slicing. Garnish with fresh parsley and serve with a side salad or roasted veggies.